Drug Development: Molecular Targets for GI Diseases

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More Books in Pharmacology See All. Foundations of Naturopathic Nutrition. In Stock. Nursing Calculations, 9E. Toxicology Handbook 3rd Edition. Fundamentals of Pharmacology. Food of the Gods.

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Herbal Antivirals. Medical Pharmacology at a Glance At a Glance. Series r. Aromatherapeutic Blending Essential Oils in Synergy. Popular Searches body by science nursing drug guide dk science book nursing care plan example pharmacology and the nursing process. The contemporary topics covered, from a mechanistic viewpoint, are relevant to gastrointestinal inflammation and motility disorders. Authoritative opinions are offered on both future research directions and potential applications for new therapies. Product Details Table of Contents.

Tepperman and B. Levine and Claudio Fiocchi. Sarna, Michel R. Briejer, and Jan A.

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National Academies Press US. British Journal of Clinical Pharmacology. BJU International. Journal of Medicinal Chemistry. Annual Review of Pharmacology and Toxicology. Nobel Lecture ". Retrieved 28 February The Lancet. Future Medicinal Chemistry.

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Drug Discovery Today. Natural Compounds as Drugs Volume I. Progress in Drug Research. Current Drug Targets. BMC Biology. Journal of Computer-Aided Molecular Design.

Drug Development

Weinheim: Wiley-VCH. Introduction to fragment-based drug discovery. Topics in Current Chemistry. Fragment-based drug discovery a practical approach. In Miller BL ed.

Dynamic combinatorial chemistry: in drug discovery, bioinorganic chemistry, and materials sciences. Chemical Society Reviews. Fragment-based approaches in drug discovery. International Journal of Molecular Sciences. Journal of Combinatorial Chemistry. Nature Reviews Drug Discovery.

Journal of Chemical Information and Computer Sciences. Journal of Natural Products. Angewandte Chemie. The handling of natural products is cumbersome, requiring nonstandardized workflows and extended timelines. Revisiting natural products with modern chemistry and target-finding tools from biology reversed genomics is one option for their revival. With the current framework of HTS in major pharmaceutical industries and increasing government restrictions on drug approvals, it is possible that the number of new natural product—derived drugs could go to zero.

However, this is likely to be temporary, as the potential for new discoveries in the longer term is enormous. Here, we review strategies for natural product screening that harness the recent technical advances that have reduced [technical barriers to screening natural products in high-throughput assays]. The growing appreciation of functional assays and phenotypic screens may further contribute to a revival of interest in natural products for drug discovery.

Molecules Basel, Switzerland. In Huxley R ed. The Great Naturalists. BMB Reports.


International Journal of Pharmaceutics. The Plant Cell. Frontiers in Plant Science. Cancer Research. Experimental Dermatology. Biochimica et Biophysica Acta. Frontiers in Immunology.


Drug Development: Molecular Targets for GI Diseases / Edition 1

In Kuntz M ed. Advances in Botanical Research. Natural Product Reports.

Finding Targets Inside the Cell: Small Molecule Drug Discovery

Gad SC Drug Discovery Handbook. Hoboken, N. Textbook of Drug Design and Discovery. Rasmussen N Baltimore: Johns Hopkins University Press.